INA105 - SchisCCA

Tahapan Penelitian : Awal
Sponsor:
Mitra Pelaksana:
INA-RESPOND Network
No Registry
Tanggal Input Registry : 14-03-2019

01-07-2019
To estimate the accuracy of the schistosomiasis point-of-care circulating cathodic antigen (POC CCA) urine test for monitoring Schistosoma japonicum infection.
1. To update existing epidemiologic, risk factor and mapping of human, snail and animal infections. 2. To identify high infection risk areas with the updated data. 3. To assess correlations between spatial parameters and other risk factors related to human schistosome infections. 4. To assess rates of positive testing by POC-CCA rapid urine test, Kato Katz stool microscopies, serology, and molecular methods (PCR). 5. To evaluate the impact of abnormal urinary findings, i.e. hematuria and markers of urinary tract infections, to POC-CCA rapid urine test results. 6. To evaluate the efficacy of praziquantel administered through local primary health centers (Puskesmas). 7. To estimate the prevalence of soil transmitted helminths infection (STH), i.e. roundworms (Ascaris lumbricoides), whipworms (Trichuris trichiura), and hookworms (Necator americanus and Ancylostoma duodenale) in this population.
 
INA105 - SchisCCA
Validation of the Schistosomiasis Point-of-Care Circulating Cathdic Antigen (POC-CCA) Rapid Urine Test for Qualitative Detection of Schistosoma japonicum
Observasional
N/A
10000
 

Inclusion Criteria:

1. Reside in schistosomiasis affected areas for at least 8 weeks. 2. Age ≥2 years. 3. Provides a documented informed consent for participants’ ≥18 years old or informed consent by parents/legally accepted representative (LAR) or assent for minor participants prior to the study procedures. 4. Willing to comply with the study procedures. 5. Agrees to the collection and storage of specimens.

Exclusion Criteria:

None
 
LB.02.01/2/KE.027/2019
N/A
N/A
INA-RESPOND
dr. Muhammad Karyana, MKes, Telp. +622142879189 email. mkaryana@ina-respond.net