Comparison of Intravenous Ibuprofen and Ketorolac for Acute Musculoskeletal Pain from Various Etiologies

Tahapan Penelitian : Awal
Sponsor:
Mitra Pelaksana:
Bethesda Hospital, Yogyakarta, Indonesia
No Registry
INA-F3KQ3DK
Tanggal Input Registry : 01-12-2019

09-12-2019
Visual Analogue Scale (vas) for pain intensity that measured in 1 hour and every 8 hours after the medication administration for total 48 hours after admission.
1. Physician global assessments 2. Patients global assessments 3. Total rescue medication after 48 hours of the medication administration using VAS 4. Safety profile of the medication 5. Consumption of rescue pain medication in 48 hours after the initiation of medication administration.
 
Comparison of Intravenous Ibuprofen and Ketorolac for Acute Musculoskeletal Pain from Various Etiologies
Comparison of Intravenous Ibuprofen and Ketorolac for Acute Musculoskeletal Pain from Various Etiologies
Eksperimental
This is a quasi experimental, non randomized, non equivalent, active comparator, open label study. The intervention in this study is an intravenous 800 mg ibuprofen. The intravenous ibuprofen will be given every 12 hours. We will need 4 intravenous ibuprofen injection for every patient. There will be a total need of 120 IV ibuprofen injection for this study. The control in this study is an intravenous 30 mg ketorolac. The ketorolac injection will be given every 12 hours.
60
 

Inclusion Criteria:

Inclusion criteria : 1. Male and female 2. > 18 years old 3. Acute moderate to severe (VAS > 4) musculoskeletal pain from various etiologies. 4. In-patients at Bethesda Hospital, Yogyakarta, Indonesia. 5. No consumption of any Non-steroid Antiinflammatory Drug (NSAID) 3 hours before the study. 6. Alert, cooperative, able to communicate their pain.

Exclusion Criteria:

Exclusion criteria : 1. Subjects with significant renal and liver problem. 2. Subjects with known hypersensitivity with either ibuprofen or ketorolac. 3. Pregnancy and breastfeeding patients. 4. Patients that enrolled any clinical trial within a month. 5. Unwillingness to join the study.
 
1094/C.16/FK/2019
Not Applicable
Not Applicable
02/PZ/XII/2019
dr. Rosa De Lima Renita Sanyasi